Monday, March 13, 2017

toxicology

Toxicology
Toxicololgy is a major health role that everyone needs to be aware of and how harmful it can be. Lots of everyday items can be toxic to you, your children or pets. Examples are laundry detergent, hand sanitizer, and many more everyday uses that if in the wrong hands can cause a lot of damage to oneself and toxicate someone, which brings up many health risks and potentially death. The word toxicology can be broken down into two words which help define its meaning. The first part of the word is toxic, meaning death, very aggressive, harmful substance that can cause many harmful events to occur due to the unwanted toxic substance. The second part of the word is ology- meaning the study of so and os. In this case it’s the study of toxics. People study how chemicals can bring upon harmful and problematic situations for living things, thus for, being very important for people to be aware of what is toxic to protect ourselves and onself from intaking a toxic item or what tod o if that would happen.





Toxic substances/items can be brought into our body in a few different ways. These different ways could be anything from just breathing in a toxic gas that is polluted in the air, you could easily inhale and it enters the body. Another way is by contact. This could be your skin or eyeball, anything that makes physical contact with your outside of your body that is harmful/toxic to you. Another more common way for children and pets is by swallowing and/or ingestion of the toxic substance. Many kids eat laundry detergent pods because it looks like candy and smells great, but those are highly toxic to the human body and especially such a young, sensitive body. Lastly, one could be injected by a substance that is toxic and that will go straight into your bloodstream and cause immediate affects to oneself.












Biotransformation is alterations that happen inside the body due to most likely a drug by enzymatic activity. There is two phases that this biotransformation will undergo during its time within the body. Phase one of this biotransformation process has  few events that usually occur, such as, oxidations, reductions, and hydrolysis reactions. In phase one, it introduces what will be the functional group and where the center that’s actively ready for the sequential conjugation preparing for phase two. Phase two is ready once that active center is ready/ the functional group, which is the site for that conjugation that holds the endogenous substance, will go to.

















Another correlated event that we keep an eye on with toxicology is the dose-response relationship. This simply means what are the effects when you get a very low amount/dose of that toxic substance and the difference when you get a very high dosage of that toxic substance and how that affects you. This dose-response has been studied with many common items and you can find on labels warning if you have a certain amount of this product consumed this and this will occur. Dose-response is important for people who care for those who have been affected with a toxic item.








Another term that is correlated with toxicology is LD50, also known as lethal dose. This simply means the amount that is consumed from a toxic substance that kills fifty percent of the test sample. So again with labels, you could see this on chemical labels saying if you consume one third of this bottle it will be fetal to oneself. And this is very important when dealing with any kind of chemicals that are used for machinery, pools, cars, etc to know if in some case you were to consume it and to be educated on how much would take your life away.





There is a certain criteria so to speak for what classifies as toxicology. Those would be factors related to exposure, biologic factors and chemical factors help influence the meaning of toxicology.




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